The emergence of high-throughput next-generation sequencing technologies has revolution is ed genomic research in recent years. The current NGS plat form shave allowed in depth transcript to mesequencing of nearly all plant species, even those with complex genomes, those without genomic or EST sequences, and those in which genome sequencing is not cost-efficient. Interestingly, these approaches have allowed to generate millions of short cDNA reads that can be assembled to recover full-length genes, novel transcripts, splicing variants, and expressed Chlorprothixene single nucleotide polymorphisms in different plant tissues or under various Testosterone cypionate stress conditions. In addition, transcriptome sequencing enables absolute measurement of gene expression, which, compared to relative quantification using microarrays, offers more useful data and greater accuracy. In recent studies, transcriptome sequencing has been applied to explore molecular pathways affected during plant-pathogen interactions in plant species such as citrus, Arabidopsis, potato, cotton, Nicotiana tabacum, and Paulownia. The aims of this study were to generate detailed transcript to mesequences that can be used in future genomic and transcriptomic studies of Mexican lime and to identify genes that are differentially expressed during phytoplasma infection. By comparison of transcript levels of healthy and infected Mexican lime trees, we identified 2,805transcriptswhoseexpression was deregulated due to infection by Ca.P. aurantifolia. We thus provide evidence on the mechanisms behind the interaction of Mexicanlime with Ca. P.aurantifolia. Filamentous inclusions of the microtubule-associated protein, tau, define a variety of neurodegenerative diseases called tauopathies. The autosomal dominant tauopathy, Frontotemporal dementia and parkinsonism linked to chromosome 17, results from mutations in the tau gene, demonstrating that tau is sufficient to cause neurodegeneration. Alzheimer��s disease is characterized by both tau aggregates, known as neurofibrillary tangles, and extracellular plaques composed of beta-amyloid.