Therefore, we conclude that the Se14 locus is identical to the Os03g0151300 locus, and se14 is a loss-of-function allele at the Se14 locus. The Se14 gene encodes a JmjN and JmjC domaincontaining protein with four copies of the C2H2-type ZnF domain. ChIP assays showed that trimethylated H3K4 of HS112 was specifically increased at the upstream region of the RFT1 chromatin. Thus, Se14 is considered to be a key gene in controlling H3K4 trimethylation states in the RFT1 chromatin, thereby acting as a suppressor of RFT1 under long day-length conditions. Chromatin structure is important for the accessibility of factors and cofactors that regulate gene expressions. Histone lysine methylation has garnered a lot of attention due to the complicated role it plays in the epigenetic modification that both activates and suppresses gene expression. The methylation state of H3K4 primarily has an activating function of gene expression involved in flowering time control. Recent ITSA-1 studies on Arabidopsis have suggested that JmjC domain-containing proteins function as histone demethylases. They are capable of demethylating all of the mono-, di- and tri-memethylated lysines of histones. It has been reported that Atjmj4 and ELF6, which encode a JmjCcontaining protein resembling those of the human JARID1 family, function as H3K4 demethylases of FT histones and suppress FT expression. Yang et al. reported that overexpression of JMJ15, which is a member of the H3K4me3 demethylase JARID1 family, resulted in obvious early flowering due to the reduction in H3K4me3 at the FLC locus associated with the suppression of FLC transcription levels. It is therefore believed that JmjC domaincontaining proteins are crucial factors for mediating the IC 261 H3K4me state and regulating gene expression involved in flowering time control. Chen et al. demonstrated that, in rice, a loss-of-function mutation of a JmjC domain-containing protein, JMJ703, affected stem elongation and plant growth, which may be related to the increased expression of cytokinin oxidase genes due to failure of demethylation of H3K4me marks. Therefore, the H3K4me mark is important for the epigenetic remodeling of the chromatin structure that regulates rice growth.