Supports the utility of implementing multiple behavioral tasks for measuring impulsivity because of its conceptual complexity

This finding is also in line with the maladaptive behavior of OCD patients involving excessive aversion to slight risk, which is commonly thought to result from their perception of situations as highly threatening. We found that the OCD participants showed significantly higher total scores than controls did on the attentional and motor subscale scores but not on the non-planning subscale of the BIS11. Most previous studies have also consistently reported higher total and attentional subscale scores of the BIS-11 in OCD. In terms of motor subscale of BIS-11, there are some controversies. Contrary to ours, some previous studies could not find any difference of motor impulsiveness of BIS-11 between OCD patients and controls. However, in one recent Korean study, the motor impulsiveness of the BIS-11 in OCD patients was significantly higher than in controls and was correlated with hoarding or aggressive/checking dimensions of obsessive-compulsive symptoms. In another Korean study, XAV939 284028-89-3 Although the difference in motor impulsiveness between OCD patients and controls did not reach statistical significance, the effect size was bigger than in ours, which means that the main reason for their being no difference in motor impulsiveness was the small sample size. Consistent with previous findings, our study showed no difference in non-planning impulsiveness between OCD and control participants. To our knowledge, this is the first study of OCD that used the SST, DDT, and BART altogether. All of the three behavioral measures of impulsivity demonstrated differences between groups. In OCD subjects, the performances of the SST, DDT, and BART were not correlated with each other. This finding suggested that there were no associations between behavioral disinhibition, impulsive decision making, and unduly risk taking. Several investigations that used multiple measures of impulsivity simultaneously in the study of other psychiatric disorders, such as substance use disorders or impulse control disorders, also showed inconsistent profiles between measures. In our study, increased behavioral disinhibition and impulsive decision making but decreased risk taking were observed in OCD subjects. Such a result might be possible when each task reflects a distinct underlying process. The null correlations between task parameters are consistent with some prior investigations, which also suggest that various assessments of impulsivity are distinct from each other and that there might be different neurobiological mechanisms underlying each process. Although speculative, it is conceivable that each process could contribute to the OCD phenotype in different ways. In the simple case of a patient with pathologic doubt and checking, risk aversion could lead to a greater preference for avoiding risky situations, whereas a concomitant inability to wait for tension relief may provoke safety behaviors, and the inability to stop already started behaviors leads to repeating those behaviors.

Leave a Reply